There's no shortage of good connecting options for Chicago to Zakynthos business class. American's Flagship Business gets you a proper lie-flat suite with Casper bedding and Flagship Lounge access at O'Hare, typically routing through a European gateway. United's Polaris product is similarly strong — lie-flat pods in 1-2-1 configuration with Saks Fifth Avenue linens, usually connecting via Newark or a European hub. If you want a genuine step up in privacy, British Airways' Club Suite includes a closing door at every seat, which matters on an overnight eastbound leg when you actually want to sleep. Lufthansa's newer Allegris suites on the A350 are worth seeking out specifically — ask your Travel Manager to confirm the aircraft type, since older 747s and A340s still run older seats. Air France, KLM, Turkish, LOT, SAS, Finnair, and Iberia round out the field, each connecting through their home hub (Paris, Amsterdam, Istanbul, Warsaw, Copenhagen, Helsinki, Madrid), and all offer lie-flat 1-2-1 seating that's a real improvement over domestic-style business cabins. Turkish's DO&CO catering and Istanbul lounge are standouts if you don't mind a slightly longer connection, and Finnair's Helsinki routing tends to be one of the shorter overall itineraries geographically.